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Description:
A genetic bowel cancer risk test analyses your DNA to assess your likelihood of inheriting a genetic condition that significantly increases your risk of developing bowel cancer. It is used to Identify individuals with a higher chance of developing bowel cancer due to specific inherited gene mutations. Early detection allows for more intensive screening and potentially preventive measures to reduce the risk.
Gene List:
Adenomatous Polyposis Coli Gene (APC) - Plays a critical role in regulating cell growth and preventing uncontrolled cell division.
Epithelial Cell Adhesion Molecule (EPCAM) - Codes for a protein critical in various cellular functions, particularly in epithelial cells lining our organs and body surfaces.
MLH1 - The MHL1 gene, short for MutL Homolog 1, is a crucial player in maintaining genomic stability within cells.
MSH2 - short for MutS Homolog 2, is a vital component of the DNA mismatch repair (MMR) system within cells. MMR acts as a cellular quality control process, ensuring the accuracy of our genetic information during cell division.
MSH6 - The MSH6 gene, standing for MutS Homolog 6, is an essential player in a cellular process called DNA mismatch repair (MMR). MMR acts like a meticulous proof-reader, ensuring the accuracy of our genetic information during cell division.
MUTYH - MUTYH gene provides instructions for making an enzyme called MYH glycosylase, which plays a crucial role in DNA repair. Mutations in this gene can lead to a condition called MUTYH-associated polyposis (MAP).
PMS2 - The PMS2 gene, also known as PMS1 Homolog 2, is a critical player in a cellular process called mismatch repair (MMR). MMR acts like a quality control check, ensuring the accuracy of our genetic information during cell division.
PTEN - The PTEN gene, which stands for phosphatase and tension homolog, plays a critical role in regulating cell growth and division. It acts as a tumour suppressor gene, meaning it helps prevent cells from multiplying uncontrollably and forming tumours.
SMAD4 - SMAD4, short for SMAD family member 4, is a protein encoded by the SMAD4 gene. It's a critical player in a signalling pathway called the transforming growth factor-beta (TGF-β) pathway, which regulates various cellular processes like growth, differentiation (specialization), and cell death.
STK11 - The STK11 gene, also known as LKB1 (liver kinase B1), plays a vital role in regulating cell growth, polarity (orientation within tissues), and metabolism. It functions as a tumour suppressor gene, acting as a safeguard against uncontrolled cell division and cancer development.
Estimated Turnaround times:
6 Weeks
Note:
This service is only available to the age of 13 and above.
During booking, only a £30 deposit is required, which will be deducted from the total cost. The remaining payment will be collected at a later stage.
Any cancellation, rescheduling, or missed appointment within 48 hours of the scheduled time will result in the loss of the £30 deposit. If you wish to reschedule, a new £30 deposit will be required to secure the new appointment.