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What is it?
Polynucleotide treatment is a non-invasive, injectable skin therapy aimed at rejuvenating and repairing the skin. It uses polynucleotides—naturally derived DNA fragments—to stimulate cell regeneration, improve skin hydration, and enhance elasticity. These agents help to attract water molecules to the skin, boosting hydration levels while also promoting collagen production.
For this reason, polynucleotides are defined as bio-restructuring compounds, that not only nourish and protect cells, but above all stimulate an increase in production and efficient reproduction thus considerably reducing the aging process.
Procedure
The procedure involves the micro-injection of a polynucleotide solution into the dermis or subcutaneous tissue using fine needles, with cannulas occasionally used for delicate areas like under-eyes to minimize bruising. A topical numbing cream is applied beforehand to ensure comfort during the treatment. The treatment is minimally invasive, with injections targeting specific areas to promote skin rejuvenation.
Product administered
We also use Lumi Eyes for our polynucleotide treatments. This specialized formula is designed to rejuvenate and repair the delicate under-eye area, providing deep hydration, reducing dark circles, and improving skin elasticity. Lumi Eyes helps stimulate collagen production and enhances skin regeneration for a refreshed and youthful appearance.
Lumi Eyes vs. Nucleofill Eyes – Comparison Table
Feature | Lumi Eyes (Dermaren) | Nucleofill Eyes (Nucleofill) |
Main Ingredient | Polynucleotides (PDRN from salmon DNA) | Highly purified long-chain polynucleotides |
Primary Purpose | Brightening, deep hydration, reducing dark circles and puffiness | Lifting, firming, biostimulation, reducing wrinkles and fine lines |
Best For | Dark circles, tired-looking eyes, dehydration | Loose skin, fine lines, mild ptosis (drooping), periocular rejuvenation |
Mechanism of Action | Deep hydration and tissue regeneration, stimulates fibroblasts to repair under-eye skin | Lifting effect through collagen stimulation, improves skin elasticity |
Hydration Effect | High | Moderate |
Lifting & Tightening | Mild | Strong |
Treatment Sessions | 1–3 sessions (4 weeks apart) | 2–4 sessions (2–3 weeks apart) |
Longevity of Results | ~6 months | ~6–12 months |
Downtime | Minimal (some swelling for 24-48 hours) | Mild swelling, possible bruising for a few days |
Needle Depth | Superficial (mesotherapy technique) | Deeper (injection into reticular dermis) |
Timeline and Expected Results
Results from Lumi Eyes treatment develop gradually. Initial improvements, such as enhanced hydration and reduced puffiness, are noticeable within 2–4 weeks. Full effects, including smoother skin, reduced dark circles, and softened fine lines, become visible at 6–12 weeks. Although you can achieve a flawless outcome in just one session, a course of 3 sessions spaced 4 weeks apart is recommended for optimal results, which typically last 6–12 months.
What does it help with?
Anti-aging and fine lines
Dark circles and dullness
Loss of skin elasticity
Dehydration and weakened skin barrier
Skin texture and tone concerns
Appointment duration
60 mins
Precautions and possible side effects
Swelling after the procedure is a common response to many aesthetic treatments. This occurs due to the needle's penetration and the volume of product placed just beneath the skin under the eyes. However, every client reacts differently—some may not experience any swelling, while others might notice puffiness. In most cases, any swelling should gradually subside within 7 to 14 days.
Note
This service is exclusively for individuals aged 18 and over.
During booking, only a £30 deposit is required for the initial consultation, which will be deducted from the total treatment cost. The remaining payment will be collected at a later stage.
If you require treatment for multiple areas, please fill out an enquiry form by clicking here, and we can offer you a more cost-effective quote.
Furthermore, Any cancellation or rescheduling within 48 hours before the appointment will incur a charge of 20% of the total service cost, and missed appointments will be deemed non-refundable.