Varicella zoster virus (VZV) commonly causes chickenpox (varicella). Testing for varicella zoster antibodies is significant for several reasons. It helps diagnose active infection, confirm immunity, and determine the need for vaccination or antiviral treatment. Testing is essential for individuals with suspected varicella or shingles, pregnant women, healthcare workers, and those at risk of severe complications. EDTA (Lavender Top) It aids in controlling outbreaks, protecting vulnerable populations, and preventing the spread of VZV.