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Polynucleotides (Nucleofill)

From £179

What is it?

Polynucleotide treatment is a non-invasive, injectable skin therapy aimed at rejuvenating and repairing the skin. It uses polynucleotides—naturally derived DNA fragments—to stimulate cell regeneration, improve skin hydration, and enhance elasticity. These agents help to attract water molecules to the skin, boosting hydration levels while also promoting collagen production.


For this reason, polynucleotides are defined as bio-restructuring compounds, that not only nourish and protect cells, but above all stimulate an increase in production and efficient reproduction thus considerably reducing the aging process

What does it help with? 

  • Dull skin

  • Fine lines and wrinkles

  • Dehydration

  • Skin texture and tone concerns

Product administered

We use the Nucleofill range for our polynucleotides treatment, which are various solutions designed to address various skin  and hair concerns, offering benefits such as deep hydration, antioxidant protection, and stimulation of collagen production. The different formulations include:


  • Nucleofill 20 (Medium): A mild biorevitalizer that hydrates, boosts elasticity, and improves skin tone and texture.

  • Nucleofill 25 (Strong): A gel that improves skin elasticity, tightness, and helps prevent wrinkles, specifically designed for more mature skin.

  • Nucleofill Eyes (Soft Plus): A non-surgical injectable treatment that improves the appearance of the skin around the eyes. It is designed to reduce dark circles, eye bags, and wrinkles.

  • Nucleofill Hair (Medium Plus): Formulated to improve the health of hair follicles, this product addresses hair thinning and androgenetic alopecia.


Polynucleotides - Comparison Table

Below is a comparison of the most widely used polynucleotide treatments, outlining the specific features and best uses for each:


Polynucleotides – Comparison Table


Feature

Lumi Eyes

Nucleofill

Rejuran

Plinest

What it does

Hydrates and brightens under-eyes

Firms and rebuilds ageing skin

Repairs and heals damaged skin

Improves skin texture and hydration

Best for

Dark circles, tired eyes

Loose skin, fine lines

Acne scars, sensitive or damaged skin

Early ageing, dull or dry skin

Under-eye use

Yes (main use)

Yes

Yes

Yes

Lifting effect

Low

High

Mild

Mild

Skin repair

Mild

Moderate

Strong

Moderate

Downtime

Very little

Mild swelling/bruising

Slightly more (small bumps possible)

Very little

How long it lasts

4–6 months

6–9 months

Around 6 months

4–6 months


Timeline and Expected Results 

Typically, the effects of Polynucleotide treatments last for about 6-9 months and although some improvement may be noticeable after 2-3 weeks, the full effect is typically visible after 3 months.


Procedure

The procedure involves the micro-injection of a polynucleotide solution into the dermis or subcutaneous tissue using fine needles, with cannulas occasionally used for delicate areas like under-eyes to minimize bruising. The treatment is minimally invasive, with injections targeting specific areas to promote skin rejuvenation.

Appointment duration

60 mins

Note

This service is exclusively for individuals aged 18 and over. During booking, only a £30 deposit is required for the initial consultation, which will be deducted from the total treatment cost. The remaining payment will be collected at a later stage.


Please note that the discounted model price is applicable for a single session only and cannot be repeated. Any subsequent sessions will be charged at the original, full price.


If you require treatment for multiple areas, please fill out an enquiry form by clicking here, and we can offer you a more cost-effective quote.


Any cancellation, rescheduling, or missed appointment within 48 hours of the scheduled time will result in the loss of the £30 deposit. If you wish to reschedule, a new £30 deposit will be required to secure the new appointment.



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123 Commercial Road | Swindon | SN1 5PL

GPhC Registration number: 1038758

©Epicare Health Ltd.

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