What is it?
Polynucleotide treatment is a non-invasive, injectable skin therapy aimed at rejuvenating and repairing the skin. It uses polynucleotides—naturally derived DNA fragments—to stimulate cell regeneration, improve skin hydration, and enhance elasticity. These agents help to attract water molecules to the skin, boosting hydration levels while also promoting collagen production.
For this reason, polynucleotides are defined as bio-restructuring compounds, that not only nourish and protect cells, but above all stimulate an increase in production and efficient reproduction thus considerably reducing the aging process
ProcedureWhat does it help with?
Acne scars and depressed scarring
Damaged, sensitive, or compromised skin barriers
Enlarged pores
Fine lines and general skin dullness
Product administered
We use the Rejuran range for this treatment, utilising highly purified polynucleotides to intensely repair and heal the skin from within. Rejuran is particularly famous for its ability to restore damaged skin barriers and treat scarring. The different formulations include:
Rejuran Healer: The classic treatment for overall face rejuvenation, repairing damaged cells, shrinking pore size, and restoring the skin's protective barrier.
Rejuran I (Eye): A thinner, more fluid formulation specifically designed for the delicate skin under and around the eyes to reduce crow's feet, dark circles, and thinning skin.
Rejuran S (Scar): A thicker, highly concentrated gel designed to plump depressed acne scars and stimulate intense tissue healing in targeted, damaged areas.
Polynucleotides - Comparison Table
Below is a comparison of the most widely used polynucleotide treatments, outlining the specific features and best uses for each:
Polynucleotides – Comparison Table
Feature | Lumi Eyes | Nucleofill | Rejuran | Plinest |
What it does | Hydrates and brightens under-eyes | Firms and rebuilds ageing skin | Repairs and heals damaged skin | Improves skin texture and hydration |
Best for | Dark circles, tired eyes | Loose skin, fine lines | Acne scars, sensitive or damaged skin | Early ageing, dull or dry skin |
Under-eye use | Yes (main use) | Yes | Yes | Yes |
Lifting effect | Low | High | Mild | Mild |
Skin repair | Mild | Moderate | Strong | Moderate |
Downtime | Very little | Mild swelling/bruising | Slightly more (small bumps possible) | Very little |
How long it lasts | 4–6 months | 6–9 months | Around 6 months | 4–6 months |
Timeline and Expected Results
Typically, the effects of Rejuran treatments last for about 6 months. For optimal results, an initial course of 3 to 4 sessions spaced 3-4 weeks apart is often recommended.
Procedure
The procedure involves the micro-injection of a polynucleotide solution into the dermis or subcutaneous tissue using fine needles, with cannulas occasionally used for delicate areas like under-eyes to minimize bruising. The treatment is minimally invasive, with injections targeting specific areas to promote skin rejuvenation.
Appointment duration
60 mins
Note
This service is exclusively for individuals aged 18 and over.
During booking, only a £30 deposit is required for the initial consultation, which will be deducted from the total treatment cost. The remaining payment will be collected at a later stage.
If you require treatment for multiple areas, please fill out an enquiry form by clicking here, and we can offer you a more cost-effective quote.
Any cancellation, rescheduling, or missed appointment within 48 hours of the scheduled time will result in the loss of the £30 deposit. If you wish to reschedule, a new £30 deposit will be required to secure the new appointment.
.png)




